General Information
Overview
Data ID:
SAID108
GSE:
CRA006512
GSM:
SAMC703639
Species:
Mouse
Condition:
Healthy
Disease:
Tissue:
dorsal skin
Position:
not mentioned
Cells:
6022
Age:
P49
Sex:
male
Characteristics
cell type: Immune stromal epithelial tissue: skin treatment: Trichophyton rubrum genotype: CARD9 R101C timepoint: D2 post-infection
Experiment Information
Title:
Single cell gene expression profiling of CARD9 WT and R101C murine skin infected with Trichophyton rubrum
Summary:
We used scRNA-seq to understand how CARD9 R101C remodels skin immunity and cell state in response to fungal infection in a mouse model of dermatophytosis.
Overall Design:
We performed single cell RNA sequencing (scRNAseq) of skin from WT and CARD9 R101C mice infected with T. rubrum at day two (D2) and day nine (D9) post-infection (3 replicates of each WT and CARD9 R101C at each timepoint)
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