General Information
Overview
Data ID:
SAID126
GSE:
GSE155850
GSM:
GSM7754890
Species:
Human
Condition:
HS lesion
Disease:
HS
Tissue:
whole skin
Position:
not mentioned
Cells:
2214
Age:
not mentioned
Sex:
not mentioned
Characteristics
tissue: skin cell type: keratinocyte disease: HS
Experiment Information
Title:
scRNASeq data of CD45+CD3-CD19- and keratinocytes in normal and HS skin
Summary:
Hidradenitis suppurativa (HS) is a highly prevalent, morbid inflammatory skin disease with limited treatment options. The major cell types and inflammatory pathways in skin of HS patients are poorly understood. We profiled via scRNASeq myeloid cells and keratinocytes sort-purified from two healthy skin samples and two samples with HS pathology to determine major cell types and transcriptional pathways altered in HS.
Overall Design:
scRNASeq of myeloid immune cells and keratinocytes profiled in healthy appearing skin versus skin with hidradenitis suppurativa pathology
Cell Clustering
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Enrichment Analysis
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Ranked by absolute NES
Differentially Expressed Genes
p-value threshold 0.05
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Log fold change 1.0
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CellPhoneDB Cell-Cell Communication Analysis
Dynamic Analysis

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