tissue: skin from healthy donor cell type: 1:1 Ratio of CD4 Treg (CD25+CD27+) and CD4 Teffector (CD25-CD27-)
Experiment Information
Title:
scRNASeq Data of CD4 Tregs and Teffectors in HS lesional skin and healthy skin
Summary:
Hidradenitis suppurativa (HS) is an inflammatory skin disease with limited therapeutic options. CD4 T Cells have been described as more inflammatory than T cells in healthy skin. To better understand alterations within the T cell compartment, we profiled CD4 Teffector cells and regulatory T cells (Treg) from inflammatory HS skin lesions and healthy control skin via scRNASequencing.
Overall Design:
scRNASeq of Treg and CD4 Teffector cells sort-purified from enzymatically digested skin of biopsied hidradenitis suppurativa inflammatory lesions or of healthy control skin
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