General Information
Overview
Data ID:
SAID218
GSE:
GSE203262
GSM:
GSM6165463
Species:
Human
Condition:
Vitiligo Lesion
Disease:
Tissue:
whole skin
Position:
not mentioned
Cells:
594
Age:
not mentioned
Sex:
not mentioned
Characteristics
tissue: skin cell line: Suction Blisters cell type: Single cell suspension genotype: Lesional treatment: None
Experiment Information
Title:
single cell RNA-sequencing of matched lesional and nonlesional skin from vitiligo patients
Summary:
We performed scRNA-seq analyses on patient matched lesional and nonlesional skin from viitiligo patients using the 10x genomics platform to examine different cell populations and keratinocyte states that may contribute to vitiligo disease persistence.
Overall Design:
Suction blisters were generated from patient matched lesional and nonlesional skin from 7 vitiligo patients, unfortunately 1 set (Patient B) did not have sufficient cells and was excluded from analysis
Cell Clustering
Color UMAP by
Switch between fine-grained and coarse annotations
Loading UMAP…
Enrichment Analysis
Enrichment mode
Select enrichment collection
Top pathways
Ranked by absolute NES
Differentially Expressed Genes
p-value threshold 0.05
Maximum adjusted p-value
Log fold change 1.0
Minimum log₂ fold change
Cell type group
Filter by cell type
Gene logFC p-value Score Group
CellPhoneDB Cell-Cell Communication Analysis
Dynamic Analysis

Select Cell Types

Choose 2 or more cell types to analyze ligand-receptor interactions